By Stanley T. Crooke,Archie W. Prestayko
Part I is a common assessment of anti-cancer medicinal drugs as regards their motion mechanisms, pharmacokinetics, pharmacology, identified toxicities, and scientific application. those medicinal drugs comprise alkylating brokers resembling mitomycin C and nitrosoureas; plant alkaloids comparable to maytansine; antibiotics reminiscent of anthracyclines; platinum-containing complexes; antimetabolites; and hormones. half II examines the molecular pharmacology of a few significant drug periods, specifically, bleomycin and anthracycline. The textual content additionally discusses the chemistry, mechanism, and any structure-activity relationships present in those drug sessions. half III discusses intimately the scientific pharmacology of a few antitumor medicinal drugs, for instance, cisplatin and nitrosoureas. The textual content comprises the scientific purposes, biochemistry, metabolism, and using mathematical versions in reading or describing ensuing facts.
The booklet is useful for pharmacologists, molecular biologists, and scientists enthusiastic about cancer-research.
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Antineoplastic Agents: Antineoplastic Agents v. 3 by Stanley T. Crooke,Archie W. Prestayko